Trt not working

Free T3 2. Should my morning cortisol be higher? Twice per week seems to be too much. Erections seem weak in morning and sometimes I do not have a morning erection. No strength, actually weaker than before TRT. With my regimen I was at the top end of the scale in total and free testosterone and estradiol was in check with anastrazole but I felt no different as well in terms of energy, mood or libido.

Have you ever checked out your DHT levels? I think it has to be my thyroid. I can say more once I get my reverse T3 result. My theory is it may be going up again, as it has been flagged high before even using thyroid meds. It could be my ferritin being a rate limiting factor preventing my metabolism from increasing and thus my body composition will refuse to improve. This is beyond frustrating. Are all your levels optimal now?

What about thyroid? Thank you for replying. It means alot that you are in the same boat as me. What were your pre-T values and what are your values on TRT? How long have you been on TRT and do you have E2 numbers to report?

Make room for me in that boat. How are you guys injecting? M-W-F and my T is at My Dr thinks that SQ might not be for me. Where is ur thread clarkster? Here is the link to my first thread about my Pre-TRT values.

I restarted TRT in April of this year because my previous doctor referred me to her. She has proven the most helpful. Free Testosterone Direct Being that my Free T3 is only 2. The ratio I calculated is Free Testosterone dropped a bit. It was This is probably because my estradiol came up too high.

I am going to try an eighth of anastrozole twice weekly to hopefully hit my goal of 22 Estradiol. And retest in 4 weeks. I see her this Tuesday. May take longer to receive those results. Good Luck. I have a feeling rt3 will be in top of range… How is your digestion? Any stomach issues?Forum Rules. Anabolic steroids, bodybuilding discussion forums. Remember Me? What's New? Results 1 to 21 of Thread: Why doesn't testosterone replacement therapy TRT work in the long run?

Thread Tools. Why doesn't TRT work in the long run? I've seen others who are currently longer into their TRT have problems with low T. Injections just stop working, and you have to increase doses to get T levels back to normal ranges.

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I've looked at my bloodwork that I get done once a year and I notice the same trend: each year T levels drop a little bit. I still feel great now but I've noticed I feel more tired before the next injection than I did during my first year on TRT. Anyone here who's been on TRT for over a decade? How does your bloodwork look? Have you lost your libido and did you manage to fix it some way?

Unfortunately what you are saying is completely false. Testosterone from injections or testosterone that your body produces is exactly the same. Your body cannot differentiate between the two, the major advantage is that you are in control of your levels with TRT and don't have to suffer the negative symptoms from declining T as we age.

To answer your question, It doesnt. The determining factor will be when you take the test. It other words, how long after the shot. Testosterone esters has a half life. The bloodwork is done 2 weeks after the last injection Sustanonevery year the total and free T levels drop.

trt not working

It's not imagination. Something is off. I read experiences from other people who have been on TRT for longer time than me and they have gone from more frequent injections to higher doses to different testosterone medication but the one thing that holds true is that they constantly have to use higher and higher doses.

This happens for real, there is no debate about it.

When Testosterone Therapy Is Not Working?

This is Finland, by the way, not USA. As far as I know most people on TRT here get testosterone and testosterone only. If that's the problem, what is the process that takes place here?

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You should be taking cypionate or enanthate ester of testosterone. Sustanon has too many esters and half lives in it. Injecting Sustanon sust once every 2 weeks is a big part of your problem. Also, as you get older, your body is more likely to convert Test to estrogen and DHT. Which would cause your testosterone levels to show up a little lower while running the same dose.

If that's the case you should start an Aromatase inhibitor AI and not increase test dose. Increasing the testosterone would only make it worse in that case. You need to be getting blood work done that also shows your estrogen levels.Hello, this is my first post. At first I was prescribed mg every two weeks, and i was like 4 months on that but couldnt feel any change and when i tested it was on total t, so it went down a little bit compared to before starting trt.

So my doctor decided to take me to mg cypionate a week and I have been with that dosage for a month; and still dont feel any change in symptoms. I would want to know why couldnit be that it isnt it working and what should i do?

Thank you!!! You will only need about midrange TT to have healthy FT levels. You should be using gauge insulin syringes to inject your testosterone, you can inject in the shoulders and quads. You should be feeling sometime, actually you should feel worse. This will give us a better idea as to why you are still not feeling symptom relief.

Then adjustments can be made based off of labs, not assumptions. Hello man, its great to find someone with the same SHBG characteristic. I have no problem on trying by injecting every day, but i have a few questions: how long does it take to work or should i feel effects?

trt not working

How much should I inject each day? Im actually using 23 gauge, is it necessary to change it? The most important thing to me is to know how long should i expect to feel changes by injecting every day so i can try it knowing this. The SHBG testing was done prior trt. Thank you! Stick with it and then assess. Give each protocol 8 weeks. Onset of effects of testosterone treatment and time span until maximum effects are achieved. Effects on sexual interest appear after 3 weeks plateauing at 6 weeks, with no further increments expected beyond.

Effects on quality of life manifest within 3—4 weeks, but maximum benefits take longer. Effects on depressive mood become detectable after 3—6 weeks with a maximum after 18—30 weeks.

Effects on erythropoiesis are evident at 3 months, peaking at 9—12 months.Testosterone replacement therapy is steadily on the rise.

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The number of men prescribed TRT has tripled in the last decade. But there's still plenty of misunderstanding and flat-out backwards thinking on how it works, what it is, and what it actually involves.

These are the four most common issues you need to understand before beginning treatment or dismissing the idea altogether. Done right, it may be the most significant and helpful treatments of your lifetime. This is probably the most common, and most incorrect, presumption people have towards testosterone replacement. An adult male taking doctor-prescribed hormone replacement therapy to address a diagnosed medical condition and improve his quality of life is no more "cheating" than an adult male taking doctor-prescribed asthma medication to address a diagnosed medical condition and improve his quality of life.

The TRT patient's medication happens to improve lean body mass, increase libido, and have other side effects we generally consider to be positive.

That's okay. People with hypothyroidism taking levothyroxine often see weight loss when their thyroid function is brought back into working order. And people on asthma meds are often able to increase their training intensity because they don't have to worry about, you know, dying during exercise.

Nobody's attacking them for "cheating" because those are a simple result of the meds necessary to treat their conditions. Of course, we're talking about the general public and not professional athletes who participate in organizations that have specific rules about performance enhancing drugs.

For them, cheating is a valid scenario. Even in those cases, many sports do have arguably generous or vague rules for TRT exemptions for athletes who do have legitimate low T. Unfortunately, these cases are often seen with an asterisk —an athlete exploiting a loophole to gain an unfair advantage.

We're also not referring to anyone who manipulates their body before getting a blood test in the hopes of influencing the results when they otherwise wouldn't qualify. If you have to temporarily alter your training, sleep, or nutrition in the hopes of skewing your blood labs to come back revealing "low T" in order to get a script written, then understand that you're not going to be on TRT, you're going to be on a low dose steroid cycle.

That's a dick move and you're exactly the kind of patient who makes doctors reluctant to prescribe hormone therapy to guys who actually need it. If you don't have low T, then you don't have low T.

Believe it or not, it's slightly more complex than "Get doctor's prescription for testosterone, inject testosterone, live happily ever after.

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Here's a list:. If that sounds like too much of a hassle, then you're not ready to responsibly manage your condition.

Top 8 TRT Mistakes

Be an adult and do some homework before you start manipulating a cascade of hormones in your body. The goal is to maximize health and minimize side effects, not vice versa. It would be great if we could just rely on our primary physician to handle everything for us. Ideally you'd want to hear something like this:. I don't like the look of these numbers, but this is how we'll run the treatment protocol to stay ahead of any problems. Come back in four weeks and we'll see where things stand.

Unfortunately, that situation is still rare, so you need to be ready to bring your own info to the table. Even under the care of an endocrinologist or urologist, specialists who are up-to-date with the most efficient treatment methods, you are your own best advocate, and the more knowledgeable you are, the better. Cluelessly smiling and nodding as your doctor describes why your current treatment doesn't warrant the inclusion of HCG, even though know you're having issues HCG could directly address means you end up receiving inadequate care The other benefit of being an educated patient is the ability to intelligently question a proposed course of treatment that doesn't sound right.

If your doctor is ready to prescribe a dosing schedule of one injection every three weeks, that should be a red flag and you should discuss testosterone half-lives, blood concentration peaks and valleys, and a pre-emptive rather than reactive approach to side effects.If you have Low Tand you find that the treatment you received is not providing the desired results, or if everything was going along fine but then the benefits stopped coming, the information provided here should be useful to you.

When testosterone therapy is not working as you expected, there are some things that you can do to improve the results. This is in addition to contacting your prescribing doctor for further instructions. That last sentence may be the most important because if you did not go to a doctor to get your testosterone therapy that could be your first big issue.

Testosterone is a prescribed supplemental medication used to treat Low T in men and women. It is not to be utilized for any reason other than low testosterone unless medically prescribed for additional purposes. A doctor will measure testosterone along with other essential hormone levels to assess what type of treatment is required.

There are many reasons why testosterone replacement therapy is not working.

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Misdiagnosis is one of them. This can exist when a person tries to assess and treat him or herself incorrectly, or when an inexperienced physician without advanced knowledge in hormone replacement attempts to prescribe the use of testosterone to a patient.

Other medications are often required when using testosterone, especially in cases where estrogen conversion in the body is not wanted. If an estrogen blocker was not prescribed with the testosterone therapy, this could hinder the forward progress of the treatment. The reason for this is that an enzyme called aromatase is responsible for converting excess testosterone into estrogen, creating a situation of estrogen dominance if not prevented.

Another reason why testosterone therapy may not be working is an inaccurate diagnosis. This can also occur when proper blood analysis was not performed.

Ask the Doc-Gyno problem during TRT.

Low testosterone can be confused with growth hormone deficiency, and treating the wrong condition can prevent the desired results. Why is testosterone therapy not working if treatment was prescribed by a specialist?

There are times when a person may inadvertently sabotage his or her treatment through careless actions. Smoking, excessive alcohol use, not telling the doctor about any other medications, supplements, and health issues, as well as poor lifestyle choices could all interfere with the treatment results.

If testosterone replacement therapy does not work — why not start by taking a look at the instructions that you received to ensure that you are following them as prescribed.

Next up, you want to make certain that you received your testosterone from a licensed US pharmacy and did not purchase it from a company overseas. Testosterone is a highly counterfeited medication, and some internet websites are not reputable. What you have been using may not be legitimate, high-quality testosterone. That is just one more reason to work with an experienced hormone specialist in the US.

Once you have verified that you are following all instructions for testosterone use as directed, there are some things you can do to improve your testosterone results. First of all, if you were getting the benefits for a while, and then they stopped, your body may have reached its maximum potential or it may need to have the dosage adjusted. Both of these issues are reasons to contact the prescribing doctor to determine the best action.

Do not attempt to alter your treatment on your own. This could result in adverse side effects that you do not want.As every man ages, he realizes that he often has new health issues to confront. However, what is often meant by that question is what if my low sex drive and erectile dysfunction have now become permanent conditions because of my male hormone loss?

Viewing erection-inducing medications as a means of last resort, most men with Low T would prefer to somehow increase their testosterone supply with the medically supervised use of its bio-identical equivalent and not only return to their full manhood, but their full measure of the masculine vitality that this essential male hormone supports. While the vast majority of male patients using a testosterone replacement therapy TRT program do find that treatment works for them by making a significant improvement in their deficiency symptoms, no one could honestly make the claim that all patients are going to receive the same degree of improvement.

Most men using this treatment do find that it delivers exactly what they were hoping for, which is the restoration of their full libido and sexual performance abilities.

Are you familiar with the full range of health and wellness benefits that a medically prescribed TRT program can deliver to you? If not, you should find out from a knowledgeable hormone therapy provider.

A Harvard Medical School expert recently weighed in on his treatment protocols for successfully diagnosing and treating his patients for Low T. His view is that it always works in fulfilling its therapeutic mission, which is to replace the male hormone supply of a patient who is no longer producing adequate amounts naturally. Yet he also stresses how important using the correct dosage is in achieving substantial physical and psychological improvements. A doctor who is inexperienced in prescribing TRT is probably not going to be as adept at understanding what the ideal dosage is for any individual patient.

It takes experience as well as specialized medical knowledge of the human endocrine system to get the dosage of bio-identical hormones exactly right. Those unrealistic expectations we mentioned often come from reading what people are saying about their own experiences with TRT online. Thinking that testosterone therapy is going to transform you into a modern-day Charles Atlas or Arnold Schwarzenegger is totally unrealistic.

The things that you might come across online saying that this is possible are not presently the actual facts.

trt not working

It is also not realistic to expect that treatment is going to make you feel, look and act 20 years old again, especially if you are of retirement age. Here are some of the realistic and very worthwhile benefits that you can expect to receive from using doctor prescribed testosterone therapy:. The best way to get TRT right is to find the right medical provider to administer it. If a person has never had any reasons for seeing an endocrinologist or hormone replacement specialist, it can be more than a little confusing to figure out how to find the right provider.

Naturally, most people want to find a provider that will be convenient for them to get to — and they might not realize that there are highly qualified online medical providers of TRT like Nexel Medical that provide prescription hormone replacement programs to their patients on a local basis. This means that you can find your provider online; contact them from your home or office, either by phone or email; have your testosterone levels blood test performed at a medical testing facility in your area; get your medical exam from one of our doctors that is located near you; and once you have received your prescription for therapy, you can convenient order your prescribed treatments from a secure online pharmacy that we can vouch for.

Using a medical provider with specific expertise in prescribing TRT is the right way to ensure that your program has the best possible chance of delivering the therapeutic results that you and your doctor desire. So instead of taking chances, take just a few minutes and talk to Nexel Medical about using our streamlined and very convenient process for receiving properly prescribed testosterone replacement therapy.

Get Started Now. Nexel Medical.Forum Rules. Anabolic steroids, bodybuilding discussion forums. Remember Me? What's New? Results 1 to 22 of Thread: Testosterone replacement therapy TRT not working anymore need help please! Thread Tools. TRT not working anymore need help please!

Hello, I'm new to this forum and I'm beginning to feel extremely desperate and I'm looking for some help. I have suspected of having low T for awhile I went to a Endocrinologist about 6 months ago who misdiagnosed me with cushings disease then came back and said it was low T.

My T was and I'm 20 years old. My estrogen was a My endo then put me on 50mg of Cypionate once a week. I decided to go to my brother in laws doc who specializes in Hormone therapy. He immediately put me on an estrogen blocker.

HCG and. I felt good fr the first two months or so and in the last 3 weeks I've been declining to where I don't feel its working anymore. I never was able to fully get out of depression and it has taken a dive lately and I'm extremely depressed and feel like if this doesn't work I'm not sure what' next. In addition, my joints have started hurting again like it did before I started TRT.

I called my doc and he told me to wait days from last day of taking medicine and go get blood draw to check T, Estrogen, and thyroid. Why do you think it isn't working anymore? What should I do? Your joints hurting could definitely be a symptom of your E2 being too low, along with being depressed. You're taking a pretty low dose of test, so you may not even need the Aromatase inhibitor AI. Everyone is different, I take mg a week and don't need the Aromatase inhibitor AI. I think you should do the lab tests asap and go from there.

Don't make any changes until you see the bloodwork. Make sure the E2 test is the sensitive assay. I second that I'm taking an Anastrosle Estrogen Blocker of. Thank you for the quick response I appreciate it I don't like anti-depressants and I've never had a problem with depression or anxiety until the low testosterone stuff started happening and I don't want to talk to a counselor if there's a correlation with TRT.

Sorry if I double posted. Sorry Anastrosle is. That's wayyyyyyyyyyyyy too much. Edit theres a big difference between 75mg and.